Myosin Resource Page

A compilation of useful myosin resources.

Local Pages:

• NEW! Myosin diversity: slaying the chimæra A short article describing the implications of the genome projects for myosin diversity.
• Myosin Classes A clickable table summarising the main features of the 17 myosin classes and outliers. Links to other pages on this site and relevant databases.
• Myosin Domains A list of the most important domains identified in myosin sequences.
• Myosin Diseases and Mutations Diseases and mutations of mouse and man that involve myosin genes.
• Myosin Complements The complete suite of myosin genes of different organisms. How many myosins does it take to be a yeast?
• NEW! Myosin genes from the Human Genome
• Myosin labs Other labs that work on various aspects of myosins. Many lab homepages have much useful information and links.
• Myosin Diversity lecture notes. An introduction to the topic of myosin diversity.

Other resources:

• The Myosin Home Page The number one stop on the web for myosin information, particularly phylogenetic trees, alignments and accession numbers. The latest phylogenetic tree is also available in PDF format from the Journal of Cell Science 113:3353-3354.There is also a chart of myosin classes. Other excellent material includes articles on a number of topics by the experts in the field, including fascinating "historical" accounts by Tom Pollard on the discovery of myosin I, and Andrew Szent-Györgyi on myosin light chains.
• Sellers lab pages including a phylogenetic tree and a chart of myosin domains.
• EF-Hand Calcium-Binding Proteins Data Library a useful resource for this family of proteins which includes myosin light chains.

References:

1. James R. Sellers (2000) BBA - Molecular Cell Research 1496(1):3-22 Myosins: a diverse superfamily [Abstract] [PDF] [Pubmed]
2. Hodge T and Cope M.J.T.V. (2000) A Myosin Family Tree. Journal of Cell Science 113, 3353-3354 [HTML] [PDF] [Tree PDF] [Tree JPEG] [PubMed]

This site will no doubt contain some errors and omissions - for which I apologise. This field is still moving so rapidly that it is hard to keep up to date. Please let me know your comments, suggestions and updates to the information.